At paragraph 6.20, the 17th edition of The Chicago Manual of Style notes that the abbreviation etc. (et cetera, literally “and others of the same kind”) and such equivalents as and so forth and and the like are preceded by a comma. In a slight departure from previous editions of CMOS, such expressions are
This month’s workout, “Commas with Quotations and Questions,” is taken from CMOS 17, paragraphs 6.40–42. Advanced editors might tackle the questions cold; learners can study paragraphs 6.40–42 of the Manual before answering the questions.
Many quotations end with a period or comma:
“He’s gone.” She turned away.
“Indeed,” he said.
Others end with a question mark or exclamation point, in which case